Heart Disease

Stress at work linked to heart disease

overworked manPeople who have highly demanding jobs and little freedom to make decisions are 23 per cent more likely to experience a heart attack compared with their counterparts without such work stress, according to a study of nearly 200 000 people from seven European countries.

Professor Mika Kivimäki from UCL Epidemiology & Public Health led the research which is published today in The Lancet.

The pooling of published and unpublished studies allowed us to investigate the association between coronary heart disease (CHD) and exposure to job strain – defined by high work demands and low decision control – with greater precision than has been previously possible,” explains Professor Kivimäki.

Our findings indicate that job strain is associated with a small, but consistent, increased risk of experiencing a first CHD event such as a heart attack.

Previous studies examining the impact of job strain on CHD have been inconsistent in their findings, limited in scope, and plagued by methodological shortcomings including publication bias and reverse causation bias.

In this collaborative meta-analysis, Professor Kivimäki and colleagues analysed job strain in employees without CHD who participated in 13 European national cohorts conducted in Belgium, Denmark, Finland, France, Netherlands, Sweden, and the UK between 1985 and 2006. All participants completed questionnaires at the start of the studies to assess job demands, excessive workload, the level of time-pressure demands, and their freedom to make decisions.

People who have highly demanding jobs and little freedom to make decisions are 23 per cent more likely to experience a heart attack compared with their counterparts without such work stress, according to a study of nearly 200 000 people from seven European countries.

Professor Mika Kivimäki from UCL Epidemiology & Public Health led the research which is published today in The Lancet.

“The pooling of published and unpublished studies allowed us to investigate the association between coronary heart disease (CHD) and exposure to job strain – defined by high work demands and low decision control – with greater precision than has been previously possible,” explains Professor Kivimäki.

“Our findings indicate that job strain is associated with a small, but consistent, increased risk of experiencing a first CHD event such as a heart attack.”

Previous studies examining the impact of job strain on CHD have been inconsistent in their findings, limited in scope, and plagued by methodological shortcomings including publication bias and reverse causation bias.

In this collaborative meta-analysis, Professor Kivimäki and colleagues analysed job strain in employees without CHD who participated in 13 European national cohorts conducted in Belgium, Denmark, Finland, France, Netherlands, Sweden, and the UK between 1985 and 2006. All participants completed questionnaires at the start of the studies to assess job demands, excessive workload, the level of time-pressure demands, and their freedom to make decisions.
UCL

Less education linked to ageing

Telomer-structure

Three-dimensional molecular structure of a telomere (G-quadruplex) Wikepedia

People who leave education with fewer qualifications may age more quickly, according to new research.

A group of scientists led by BHF Professor Andrew Steptoe separated study participants into four groups, according to how long they stayed in education.

The researchers found that people who left education earlier had shorter ‘caps’, called telomeres, on the ends of their DNA – a marker of ageing in cells. As we age we’re more at risk from heart disease. [continue reading…]

Smoking, eating fattening foods and not getting enough exercise are all lifestyle habits that can lead to poor health and cardiovascular disease – more so if you have a family history. But researchers at UT Southwestern Medical Center have found that women don’t change these habits as often as men, even when they have relatives with heart disease.

The scientists, reporting in the September issue of the American Heart Journal, found that women with a family history of heart disease are less likely than men to change habits such as smoking and infrequent physical activity. They also are more likely to engage in lifestyle choices that increase their risk of heart disease than are women who did not report a history of heart disease. [continue reading…]