medication

The Nocebo Effect

Time has an interesting article on the Nocebo effect, The Flip Side of Placebos: The Nocebo Effect by John Cloud

Exactly why the placebo and nocebo responses arise is a puzzle, but a fascinating article in Wired magazine noted earlier this year that the positive placebo response to drugs has increased during clinical trials over the past few years. The article speculated that drug advertising — which exploded after 1997, when the Food and Drug Administration began allowing direct-to-consumer ads — has led us to expect more from drugs. Those expectations, in turn, have made us feel better just for popping a pill. (Placebo responses can also occur simply when you book appointments with doctors or psychotherapists.)

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Source: Time

man-drinking-beer1The New Scientist reports that contarty to traditional beliefs about the effects of booze on male performance, new research from the University of West Australia is suggesting that moderate drinking actually protects against impotence in the long term – perhaps for the same reason a glass or two of wine a day cuts the odds of suffering from heart disease. Click to continue reading

Source: New Scientist
Image Credit: iStockphoto.com

Schizophrenia drug’s dosage drives success

The Vanderbilt physician who in the late 1980s established the antipsychotic drug clozapine as the gold standard for treating patients with treatment-resistant schizophrenia has improved on his own research.

Herbert Meltzer, M.D., director of the Schizophrenia Program in the Department of Psychiatry, and colleagues have shown that the success of clozapine in treating this population was not due to the unique pharmacologic features of the drug itself, but the fact that it was used at higher doses than what is used to treat patients with schizophrenia who respond well to antipsychotic drugs. Clozapine is rarely used for the 70 percent of patients whose psychotic symptoms respond well to a wide array of other antipsychotic drugs. [continue reading…]