First top 10 list for antidepressants

Researchers rank 12 common antidepressants on efficacy, acceptability. By looking at 117 studies of the 12 most popular antidepressants, researchers ranked the top 12 drugs in the journal The Lancet. Depression is a major cause of disability worldwide, and the need for treatment options, whether they be antidepressant drugs or psychological interventions, is correspondingly great. A range of clinically-proven antidepressants is available, and this multiple treatments meta-analysis sought to draw conclusions from the many randomised trials in which drugs have been studied against active comparators. Weighing systematically the evidence available on both efficacy and tolerability, the authors suggest that sertraline and escitalopram might be appropriate first-choice treatments.
Efficacy:
1. Mirtazapine (Remeron)
2. Escitalopram (Lexapro)
3.Venlafaxine (Effexor)
4. Sertraline (Zoloft)
5.Citalopram (Celexa)
6. Buproprion (Wellbutrin)
7. Paroxetine (Paxil)
8. Milnacipran (Savella)
9. Fluoxetine (Prozac)
10. Duloxetine (Cymbalta)
11. Fluvoxamine (Luvox)
12. Reboxetine (Vestra)
Acceptability:
1. Sertraline (Zoloft)
2. Escitalopram (Lexapro)
3. Buproprion (Wellbutrin)
4.Citalopram (Celexa)
5.Fluoxetine (Prozac)
6. Milnacipran (Savella)
7. Mirtazapine (Remeron)
8. Venlafaxine (Effexor)
9. Paroxetine (Paxil) 1
10. Duloxetine (Cymbalta)
11. Fluvoxamine (Luvox)
12. Reboxetine (Vestra

Source: The Lancet, ABC News
Image Credit: Tom Varco