Different anti-aging treatments work together and add years of life
The combination of two neuroprotective therapies, voluntary physical exercise, and the daily intake of melatonin has been shown to have a synergistic effect against brain deterioration in rodents with three different mutations of Alzheimer’s disease.
A study carried out by a group of researchers from the Barcelona Biomedical Research Institute (IIBB), in collaboration with the University of Granada and the Autonomous University of Barcelona, shows the combined effect of neuroprotective therapies against Alzheimer’s in mice.
Daily voluntary exercise and daily intake of melatonin, both of which are known for the effects they have in regulating circadian rhythm, show a synergistic effect against brain deterioration in the 3xTg-AD mouse, which has three mutations of Alzheimer’s disease.
“For years we have known that the combination of different anti-aging therapies such as physical exercise, a Mediterranean diet, and not smoking adds years to one’s life,” Coral Sanfeliu, from the IIBB, explains to SINC. “Now it seems that melatonin, the sleep hormone, also has important anti-aging effects”. [continue reading…]
In Danville, California, the Traditions Alzheimer’s Care Unit houses 20 residents, most of who are shepherded by caregivers through scheduled activities like balloon baseball and bingo. For most residents, life is routine.
But for Lee Gorewitz, life is an odyssey.
From the moment she wakes up, Lee is on a quest for something that she can neither articulate nor comprehend. Confined by the limits of her physical boundaries, she scavenges for reminders of her old identity in the outside world.
A total immersion into the fragmented day-to-day experience of Alzheimer’s disease, You’re Looking at Me Like I Live Here and I Don’t is the first documentary filmed exclusively in an Alzheimer’s care unit, told from the perspective of someone suffering from the disease.
The film documentary airs nationally on PBS starting tonight, March 29, at 10 PM.Check your local PBS station for times in your area
A team of academic researchers has identified the intracellular mechanisms regulated by vitamin D3 that may help the body clear the brain of amyloid beta, the main component of plaques associated with Alzheimer’s disease.
Published in the March 6 issue of the Journal of Alzheimer’s Disease, the early findings show that vitamin D3 may activate key genes and cellular signaling networks to help stimulate the immune system to clear the amyloid-beta protein.
Previous laboratory work by the team demonstrated that specific types of immune cells in Alzheimer’s patients may respond to therapy with vitamin D3 and curcumin, a chemical found in turmeric spice, by stimulating the innate immune system to clear amyloid beta. But the researchers didn’t know how it worked.
“This new study helped clarify the key mechanisms involved, which will help us better understand the usefulness of vitamin D3 and curcumin as possible therapies for Alzheimer’s disease,” said study author Dr. Milan Fiala, a researcher at the David Geffen School of Medicine at UCLA and the Veterans Affairs Greater Los Angeles Healthcare System.
Pilot study suggests infrared analysis of white blood cells is a promising strategy for diagnosis of Alzheimer’s disease
Spanish researchers, led by Pedro Carmona from the Instituto de Estructura de la Materia in Madrid, have uncovered a new promising way to diagnose Alzheimer’s disease more accurately. Their technique, which is non-invasive, fast and low-cost, measures how much infrared radiation is either emitted or absorbed by white blood cells. Because of its high sensitivity, this method is able to distinguish between the different clinical stages of disease development thereby allowing reliable diagnosis of both mild and moderate stages of Alzheimer’s. The work is published online in Springer’s journal Analytical & Bioanalytical Chemistry. [continue reading…]
