The brains of individuals with major depressive disorder appear to react more strongly when anticipating pain and also display altered functioning of the neural network that modifies pain sensitivity, according to a report in the November issue of Archives of General Psychiatry, one of the JAMA/Archives journals. [continue reading…]

Image credit: Kathy James

Religious emotions and believes have often been linked to a capacity to deal with pain, as those images of Philippine men being willingly crucified during religious festivals so well demonstrate. But although changes in pain sensitivity during a religious experience are well documented, the exact psychological or/and neurological reasons of the phenomenon are unclear and, as such, have now become the aim of an investigation by a group of scientists, philosophers and psychologists from the University of Oxford. The research, to be published in the next edition of the journal Pain1, reveals, for the first time, that religion-associated pain resistance is linked to the activation of the brain right ventrolateral prefrontal cortex (VLPFC), an area associated with both cognitive down-regulation of pain and reassessment of the emotional meaning of an experience – for example by giving a neutral or even positive meaning to a noxious experience, and so making it much easier to cope with. The research contributes for a better understanding of pain coping mechanisms, and, consequently, can put us closer to new and better therapies for pain, but also might help to comprehend how cultural influences, such as religion, can affect the development and use of the different parts of the brain. And it does give an extra meaning to the saying “faith helps through life’s pains”… [continue reading…]

Previous studies have shown that women experience more severe postoperative pain and require more narcotics than men in the early postoperative period. A study featured in the September issue of Anesthesiology investigates women’s pain perception and relief after Caesarean section and the impact of genetics on these outcomes. [continue reading…]