Emotional balance is regulated by molecular factors behind stress response. When healthy people are faced with threatening situations, they react with a suitable behavioural response and do not descend into a state of either panic or indifference, as is the case, for example, with patients who suffer from anxiety.

With the help of genetic studies on mice, scientists from the Max Planck Institute of Psychiatry have discovered two opposing neuronal regulatory circuits for the generation and elimination of fear. Both are controlled by the stress-inducing messenger substance corticotropin-releasing hormone (CRH) and its type 1 receptor (CRHR1). The availability of these factors in neurons that release glutamate in brain areas of the limbic system activates a neuronal network which causes anxiety behaviour. Conversely, in dopamine-releasing neurons in the mid-brain, these factors give rise to behaviour that reduces fear. Because disorders of the stress factors may be observed in many patients with affective illnesses, the scientists suspect that the pathological alteration of the CRHR1-dependent regulatory circuits may be at the root of such emotional maladies. [continue reading…]

When it comes to rearing children, just about any parent will say that what works with one kid might not work with another. Parents use all sorts of strategies to keep kids from being cranky, grumpy, fearful or moody, while encouraging them to be independent and well-adjusted.

But which parenting styles work best with which kids? A study by University of Washington psychologists provides advice about tailoring parenting to children’s personalities.
At the end of the three-year study, the psychologists found that the right match between parenting styles and the child’s personality led to half as many depression and anxiety symptoms in school-aged children. But mismatches led to twice as many depression and anxiety symptoms during the same three years.

The study was published online Aug. 1 in the Journal of Abnormal Child Psychology. [continue reading…]

Most people worry from time to time. A new research study, led by a Case Western Reserve University faculty member in psychology, also shows that worrying can be so intrusive and obsessive that it interferes in the person’s life and endangers the health of social relationships.

These people suffer from what’s called generalized anxiety disorder (GAD), says Case Western Reserve psychologist Amy Przeworski.

Individuals with GAD frequently put social relationships with family, friends, or coworkers at the top of their lists of worries, but the negative methods they use to cope—from over nurturing to extreme detachment—may be destructive.

Przeworski and colleagues at Penn State University observed that people in therapy for GAD manifested their worries in different ways based on how they interact with other people.

In two studies the researchers found four distinct interactive styles prominent among people with GAD—intrusive, cold, nonassertive and exploitable.

Both studies supported the presence of these four interpersonal styles and their significant role in how people with GAD manifested their worrying.

“All individuals with these styles worried to the same extent and extreme, but manifested those worries in different ways,” Przeworski said.

Take the examples of two people with similar worries about someone’s health and safety. [continue reading…]